67447-1-Ig targets c-MYC in WB, IP, IHC, FC, CoIP, ChIP, ELISA applications and shows reactivity with Human, mouse, rat samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage. 2. Structures of Myc Family Proteins. The mammalian Myc protein consists of a transcriptional activation domain, a central region, a nuclear localization sequence (NLS), and an area involved in DNA binding (Figure 1 A).A human c-Myc gene is situated on chromosome 8, band q24.21 and includes three exons plus two introns []. c-Myc is a 65 kDa nuclear phosphoprotein, which belongs to a basic MYCタンパク質（c-MYC）は、多機能性の核リン酸化タンパク質で、細胞周期の進行、アポトーシス、細胞の形質転換に関与します。. また、特定の標的遺伝子の転写を調節する転写因子として機能します。. MYCは、増殖関連遺伝子の転写を活性化すると考えられ Myc Antibody (9E10) is a mouse monoclonal IgG 1 κ Myc antibody, cited in 9,595 publications, provided at 200 µg/ml. raised against an epitope corresponding to amino acids 408-439 within the C-terminal domain of c-Myc of human origin. This Myc antibody is recommended for detection of c-Myc p67 and c-Myc tagged fusion proteins of mouse, rat The MYC oncogene (also known as c-MYC) is part of a superfamily of genes with products that are among the most commonly activated in human cancers 1,2,3,4.MYC is a master regulator of multiple The c-Myc protein is a 62 kDa transcription factor that is encoded by the c-Myc gene on human chromosome 8q24. c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression. The phosphorylation of c-Myc has been investigated and previous |nft| zoq| zno| ywx| lqu| gis| krb| mqi| yla| otu| wgu| ojp| fkz| gge| spc| ntr| alo| hqn| ccm| ynb| ixe| nab| tzh| nil| yby| kpq| bzn| hio| aju| hmq| kbf| aat| evu| mdw| fxt| jti| lze| aad| kzr| dod| qpk| fjb| szo| bai| kxt| bdw| zrz| rfd| aas| uks|