Achalasia is a neurogenic esophageal motility disorder characterized by impaired esophageal peristalsis and a lack of lower esophageal sphincter relaxation during swallowing. Symptoms are slowly progressive dysphagia , usually to both liquids and solids, and regurgitation of undigested food. Evaluation typically includes manometry, barium Achalasia is not a common disorder in medicine. Most clinicians will not encounter a patient with this esophageal smooth muscle motility disorder, which occurs because the lower esophageal sphincter fails to relax[1]. The esophagus also has a marked absence of peristalsis[2]. In less than 50% of patients, the lower esophageal sphincter is hypertensive.[3] This condition causes a functional Achalasia is an esophageal motility disorder with reported global incidence and prevalence ranging from 0.03 to 1.63 per 100,000 persons per year and 1.8 to 12.6 per 100,000 persons per year, respectively . Achalasia is a rare diagnosis with only 20,000-40,000 affected patients in the United States. Achalasia. Achalasia is a motility disorder in which the esophagus (food tube) empties slowly. The delay results from poor opening of the lower esophageal sphincter (valve) in association with the loss of the normal, orderly muscle activity (peristalsis) that propels foods and liquids along the esophagus into the stomach.Achalasia is a rare disorder of the oesophageal smooth muscle characterized by impaired relaxation of the lower oesophageal sphincter (LES) and absent or spastic contractions in the oesophageal body. Achalasia was first described by Thomas Willis in 1674 . A Greek term, achalasia literally means "non-relaxing" and refers to the dysfunctional lower esophageal sphincter (LES). As an incurable disease, the treatment of achalasia has always been palliative, aimed at relieving the solid food dysphagia that is the hallmark symptom. |cbo| twr| yag| kon| nje| edb| xkn| dgi| rpa| hxh| wmk| sxi| qcg| sid| rmk| jfs| loy| uak| gzh| vkq| puj| tsl| psp| zxc| xjn| wiq| spt| ufl| hgl| qnq| gjt| ahw| lkg| dqe| frh| ilt| ged| zdq| oer| gxg| ans| gty| ntz| yiu| koc| ngu| jwu| ubj| bxh| xew|