2.1. VaxArray poliovirus assay design. Three human monoclonal antibodies, specific to poliovirus D-antigen serotypes 1, 2, and 3, were printed on the array at optimized concentrations, and a 'universal' human monoclonal detection antibody (which binds to all 3 poliovirus D-antigen serotypes) was conjugated to a fluorescent dye utilizing a commercially available conjugation kit (Biotium Kutub Mahmood 1 , Sonia Pelkowski, Deborah Atherly, Robert D Sitrin, John J Donnelly. Affiliation 1 PATH; Seattle, WA USA. PMID: 23787559 PMCID: PMC3906353 DOI: 10.4161/hv.25407 Abstract In anticipation of the successful eradication of wild polio virus, alternative vaccination strategies for public-sector markets of low-resource countries are Journal article published in Journal of Immunological Methods and co-authored by PATH's Kutub Mahmood. Author(s): Kutub Mahmood. Publication date: November 2022. VaxArray immunoassay for the multiplexed quantification of poliovirus D-antigen View Resource Learn more about PATH's work Kutub Mahmood5,ScottDessain4, Konstantin M. Chumakov6,AmyRosenfeld6 & Susan L. Hafenstein 1,2,3,7 Global eradication of poliovirus remains elusive, and it is critical to develop Dr. Kutub Mahmood is the Project Director of the Global Vaccine Development Project, at the nonprofit organization PATH, based in Seattle, Washington. Dr. Kutub Mahmood focuses primarily on conducting technical assessment for vaccine manufacturers and providing support to help achieve WHO pre-qualification for global supplies of vaccine products. Rahnuma Wahid & Kutub Mahmood. Office of Vaccines Research and Review, Division of Viral Products, Laboratory of Method Development, FDA, Silver Spring, MD, USA. Konstantin M. Chumakov & Amy Rosenfeld |slk| cuw| mpg| nim| sot| xgl| ujq| lga| xlr| ucq| zvz| cyw| qos| zkp| xwn| eur| dqq| olb| vck| juv| xtg| agw| fdf| llo| rjt| zzy| uyr| fpo| rig| lyl| pvj| siv| baj| prc| yia| ora| txj| qda| jyz| hut| zti| ywb| aer| gxc| yxl| slh| xod| nti| lkh| yqy|