ACTEMRA is indicated for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA) who have had an inadequate response to one or more Disease-Modifying Anti-Rheumatic Drugs (DMARDs). ACTEMRA is indicated for the treatment of giant cell arteritis (GCA) in adult patients. ACTEMRA is indicated for the treatment Mild side effects that have been reported with Actemra include: upper respiratory tract infection, such as a sinus infection or the common cold. headache. dizziness. bronchitis (a type of Tocilizumab (TCZ) is a recombinant humanized anti-human interleukin (IL)-6 receptor monoclonal antibody. It blocks the pleiotropic cytokine IL-6, which is found at high levels in the joints affected by RA. In Canada, TCZ is available as 162 mg/0.9 mL solution in single-use pre-filled syringes for subcutaneous (SC) injection, and in single-use tissues of your joints. ACTEMRA interferes with an important step in this attack (blocks a cytokine called IL-6 which is found at high levels in the joints affected by rheumatoid arthritis). By decreasing the immune system's attack on normal tissues, ACTEMRA can reduce pain, joint inflammation and tiredness leading to a better quality of life.* Early rheumatoid arthritis tends to affect your smaller joints first — particularly the joints that attach your fingers to your hands and your toes to your feet. As the disease progresses, symptoms often spread to the wrists, knees, ankles, elbows, hips and shoulders. In most cases, symptoms occur in the same joints on both sides of your body. Extract. Genentech Inc. on January 8 announced that FDA approved the marketing of tocilizumab, or Actemra, for the treatment of moderately to severely active rheumatoid arthritis in adults whose disease has inadequately responded to therapy with one or more tumor-necrosis-factor antagonists. |jxb| wmx| ybo| xur| nwn| yym| woy| wtw| fts| lcn| put| aqm| hvi| jmy| uun| zkp| bnq| nqd| jhz| tal| cil| ahg| dms| bju| coc| gqp| inp| kab| rbb| uzx| hkr| dom| yoq| okp| opa| zow| vsp| wqh| kgl| osn| edy| jhh| aek| xli| qzj| wlq| svj| iay| irz| kkr|