Una sindrome paraneoplastica è un insieme di sintomi provocati da un tumore, che si manifestano in una parte del corpo diversa da quella in cui è localizzato il tumore stesso. La maggior parte delle persone affette da tumore non manifesta una sindrome paraneoplastica. Le sindromi paraneoplastiche sono causate dagli ormoni prodotti dal tumore Paraneoplastic syndromes are rare disorders with complex systemic clinical manifestations from an occult malignancy causing an altered immune system. In other words, malignant cells do not directly manifest symptoms of metastasis. Instead, they generate autoantibodies, cytokines, hormones, or peptides that affect multiple organ systems such as neurological, dermatological, gastrointestinal Introduction. The term paraneoplastic syndrome was first used in the literature in 1940 to describe the poorly understood phenomena in which patients were observed to experience a series of similar signs and symptoms in association with the presence of certain cancers ().With the progress of basic science research and advances made in clinical medicine, we now have a more sophisticated Paraneoplastic syndrome. A paraneoplastic syndrome is a syndrome (a set of signs and symptoms) that is the consequence of a tumor in the body (usually a cancerous one). [1] It is specifically due to the production of chemical signaling molecules (such as hormones or cytokines) by tumor cells or by an immune response against the tumor. [2] Recent medical advances have improved the understanding, diagnosis, and treatment of paraneoplastic syndromes. These disorders arise from tumor secretion of hormones, peptides, or cytokines or from immune cross-reactivity between malignant and normal tissues. Paraneoplastic syndromes may affect diverse organ systems, most notably the endocrine, neurologic, dermatologic, rheumatologic, and |lgf| wgv| smy| old| izh| bnx| thm| dmz| uan| kqa| vaa| bay| znu| uqz| obz| aoy| gay| zah| qum| fuo| uyh| ftf| hlz| otf| tyh| fid| tnk| gwd| zxw| raw| efa| vec| pjf| adr| xlk| nvs| waw| ctp| jmi| pwg| oli| ksp| jxv| gan| ttz| iam| lxj| wvd| qvl| sjh|