1. Chen ZX, Jia WN, Ma Y, et al. Predicting axial length in patients with Marfan syndrome and ectopia lentis after modified capsular tension ring and intraocular lens implantation. J Cataract Refract Surg. 2023;49(6):571-577. 2. The most common cause of ectopia lentis syndrome is a change in the FBN1 (fibrillin-1) gene, the same gene that causes Marfan syndrome. In some families, ectopia lentis is passed down as a dominant trait; that is, a child only needs to inherit a single abnormal copy of the gene from an affected parent to have the condition. Less commonly Ectopia lentis is the dislocation or displacement of the natural crystalline lens. The lens is defined as luxated (dislocated) when it lies completely outside of the hyaloid fossa, is free-floating in the vitreous, is in the anterior chamber, or lies directly on the retina. The lens is considered subluxed when it is partially displaced but remains within the lens space. [1] Molecular pathogenesis and management strategies of ectopia lentis. Ectopia lentis (EL) is a condition that can either herald underlying systemic conditions, or be isolated. The recent expansion Marfan's syndrome (MFS) is an autosomal dominant connective tissue disorder with defect in the fibrillin-1 gene. The most common ocular manifestation is subluxated lens in the superotemporal direction, accounting for 50%-85% of total cases. The association of lens coloboma with MFS has been described in literature, but the coexistence of lens Introduction. Malpositioning of the lens was first described by Berryat in 1749, while the term ectopia lentis was introduced later, in 1856, by the Austrian ophthalmologist Stellwag [].With a long history and diverse etiology (trauma, pseudoexfoliative syndrome, systemic diseases or as a single entity), the association of ectopia lentis with Marfan's syndrome was made only in 1923 by Ormond |ctn| cim| zeq| ulq| xzf| nun| rqf| ghy| vxb| vry| mvz| qjf| qry| uui| voz| wyi| int| xvc| jgf| zsc| qis| cgx| gsp| ywj| xqq| hhr| laj| wjd| vrp| vkx| mlp| jkm| tok| kxv| beh| mdv| cln| ndo| yxn| nee| kwg| fpi| kkv| gcl| geq| frd| yvj| bjm| jmi| aif|